What is fatigue syndrome? Fatigue syndrome is another common problem for people with sleep apnea. Fatigue is different from sleepiness. Rather than a desire to go to sleep, fatigue is a sense of feeling exhausted, drained. People with sleep apnea typically feel fatigued much of the time. Often, causes of fatigue is that their apnea has been present for years and has gotten progressively worse, they are not even aware that they are more tired than normal. Or they assume that their fatigue is simply a normal sign of aging. Fatigue has been associated with sleep apnea syndrome.

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