Multiple sclerosis (MS) is a central nervous system demyelinating lesions, although its exact etiology and clinical course are not entirely clear, it mostly tends to be the trigger autoimmune mediated reactions due to viral infections, it has genetic and environmental susceptibility. The clinical symptoms and pathology are complicated and diversified, which are resulted from the focus position, scope, quantity, type, degree and course of illness in the transfer process. According to TCM traditional theory, the disease area locates in brains, spinal cord, eyes, it relate with brain, marrow, meridians, extraordinary meridians ( Du, Chong, Yang Wei, Yang Rao), Zang Fu meridians.

As MS’ pathogenesis are spinal marrow deficiency, disorder of Qi function, turbid pathogen interactions, rise and fall, the root of the treatment is to reinforce the brain, marrow and meridians, we may adjust Qi meridians and Zang Fu, expelling the pathological products to treat the symptoms, alternatively, we can dredge the turbid pathogen (for example, the five inner turbid pathogen and the sputum and body fluid, toxicity stasis), promote Qi function ascending-descending and coming in-going out, clearing the area where essence and spirit are. The differentiation and treatment should accord with the principle. During and after the hormone therapy, we may treat Yin deficiency, toxic dryness, during and after immunosuppressive therapy, we should dispose Yang deficiency and damp toxicity, plasma exchange therapy helps the decline of internal toxicity, we then deal with Yin and Yang deficiency.