1) Calcium
Studies suggest that calcium levels are lower in women with PMS and that calcium supplementation may reduce the severity of symptoms. A large study looked at 1057 women with PMS and 1968 women without PMS. Women with the greatest intake of calcium from food sources had the least PMS symptoms. Another study found that 300 mg of calcium carbonate four times a day significantly reduced bloating, depression, pain, mood swings, and food cravings.

2) Chaste Tree Berry
Chaste tree (Vitex agnus-castus) berry is one of the most popular herbs for Premenstrual Syndrome in Europe. A study published in the British Medical Journal involving 178 women with PMS found that chaste tree berry significantly reduced PMS symptoms over three menstrual cycles. Women taking chaste tree had significant improvements in irritability, depression, headaches, and breast tenderness.

The most common side effects of chaste tree berry are nausea, headache, digestive disturbances, menstrual disorders, acne, itching, and skin rashes. Chaste tree berry should not be taken by pregnant or nursing women. The safety of chaste tree berry in children or people with kidney or liver disease has not been established. 

Vitamin B6

3) Magnesium
The mineral magnesium, found naturally in food and available in supplements, has showing good preliminary results for PMS. One study examined the use of magnesium supplements or placebo in 32 women with PMS. The amount of magnesium used was 360 mg three times a day, starting from day 15 to the start of the menstrual period. Magnesium supplements were found to significantly improve PMS mood changes.

Another study used 200 mg of magnesium or placebo for two menstrual cycles. By the end of the second month, magnesium was found to significantly reduce weight gain, swelling of the hands and legs, breast tenderness, and abdominal bloating. People with heart or kidney disease should not take magnesium supplements without consulting their doctor. Side effects of excess magnesium can include upset stomach and diarrhea. It can also cause nausea, vomiting, low blood pressure, slowed heart rate, deficiencies of other minerals, confusion, coma.

4) Evening Primrose Oil
Evening Primrose oil is a plant oil that contains gamma-linolenic acid, an omega-6 essential fatty acid. Gamma-linolenic acid is involved in the metabolism of hormone-like substances called prostaglandins that regulate pain and inflammation in the body. A review of seven studies on evening primrose for PMS found that the two most well-designed studies failed to show any beneficial effects for evening primrose.

5) Acupuncture
In traditional Chinese medicine, the liver is the organ most affected by stress, anger, and frustration. Stagnation of liver energy, or "qi", by emotions, alcohol, and spicy and fatty foods can lead to PMS symptoms such as breast tenderness and abdominal bloating and cramping. Although there is no scientific evidence behind this assessment, acupuncture, exercise, expressing emotions, and breathing exercises are recommended by practitioners to relieve liver stagnation.