A physician may employ one or more of the following methods to arrive at an accurate diagnosis of Pure Red Blood Cell Aplasia:

__Patient history and physical examination to assess and understand the cause
__Evaluating the function of the extremities and testing how alert the individual is
__Examination of the heart and lungs to identify the presence of any abnormalities
__Tests to check for abnormalities with the immune response
__Tests to evaluate bone marrow function
__Cultures to identify the presence of any infection

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.