A proper and detailed diagnosis and treatment may cure chronic daily headaches. The treatment primarily focuses on reducing the pain first and then acting on the core cause of chronic daily headaches. As per the frequency of occurrence of headaches and its seriousness, the treatment is usually prescribed.

Antidepressants are usually prescribed in chronic daily headaches. These drugs treat anxiety, stress and agony in the person. It also cures sleeping disorders and help getting a sound sleep. Serotonin reuptake inhibitor (SSRI) fluoxetine and Prozac or Sarafem are mostly prescribed in such condition. A deep relaxation causes fifty percent of cure in this disease. Tricyclic antidepressants like ortriptyline (Pamelor) are widely used to treat chronic headaches.

Beta blockers like metoprolol (Lopressor, Toprol-XL), atenolol (Tenormin) and propranolol (Inderal, Innopran XL) are effective in controlling the blood pressure of the sufferer. Thus episodic migraines can be effectively controlled.

Anti-seizure medications like topiramate (Topamax, Qudexy XR, others), gabapentin (Neurontin, Gralise) and divalproex sodium (Depakote) are prescribed to prevent migraines and chronic daily headaches.

Nonsteroidal anti-inflammatory drugs like naproxen sodium (Anaprox, Naprelan) are helpful to keep the sufferer away from pain killers.

OnabotulinumtoxinA (Botox) injections are great pain relievers. It is beneficial for people who have been suffering from really long.