There is no known cure for complex regional pain syndrome (CRPS). Treatment includes a multidisciplinary approach with the aim of controlling pain symptoms. It has been suggested that when treatment is started within a few months of when symptoms begin, improvement or remission may be possible.
A combination of therapies is usually necessary including medications, physical and occupational therapy, interventional procedures, and psychosocial/behavioral management.
Medications may include:
Oral and topical pain relievers
Antidepressants or anticonvulsants
Corticosteroids
Bone-loss medications
Sympathetic nerve-blocking medications
Intravenous anesthetics (Ketamine)
Intravenous immunoglobulin
Interventional procedures may include:
Trigger/tender point injections
Regional sympathetic nerve block
Spinal cord stimulation
Epidural clonidine
Chemical or mechanical sympathectomy