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Landau-Kleffner Syndrome is suspected to be caused by a mutation within a gene, the diagnosis is likely hereditary. Genetic counseling should take place when a couple is looking to become pregnant and has Landau-Kleffner Syndrome. However, as LKS is not yet determined to have a single hereditary cause, not all genetic testing centers will test for LKS.
Major symptoms and side effects of LKS (including seizures) can be prevented with the help of medication. Symptoms usually do not last beyond adulthood. Seizures and speech can be improved with immunotherapy. Speech therapy aids in improving linguistic abilities, however, potential loss of complete linguistic ability cannot be prevented. Therapy can help children improve their language and prevent permanent impacts of the diagnosis after months or years in extreme cases.
Permanent impacts have a better chance of being prevented if symptoms are addressed as soon as possible. Speech therapy needs to be started right away for kids to have a better chance of relearning their speech. Learning sign language or special education are alternatives for those who do not want to resort to surgery. Complete seizure prevention can occur with a multiple subpial transection surgery. This option is only for rare cases that were not aided with healing alternatives.