Diagnosis of Calluses and Corns
Diagnosis is often made by looking at the corn or callus. A biopsy with microscopic evaluation can be done, but is seldom necessary. The doctor also may take X-rays of your feet or hands to look at underlying bony structures that may be the cause of the corns and calluses. The doctor may also look at the way you walk and examine your shoes.

Sometimes, a wart (a skin infection caused by virus) can have similar appearance to a callus. Therefore, it is important to have an evaluation by a medical professional if home remedies do not improve the symptoms.