Treatment of Immunoglobulin A (IgA) Nephropathy
Often ACE inhibitors or angiotensin II receptor blockers for hypertension, serum creatinine > 1.2 mg/dL, or macroalbuminuria (urinary protein > 300 mg/day) and with a target urinary protein of < 500 mg/day

Corticosteroids for progressive disease, including increasing proteinuria especially into the nephrotic range, or increasing serum creatinine level

Corticosteroids and cyclophosphamide for proliferative injury or rapidly progressive GN

Transplantation rather than dialysis if possible

Normotensive patients with intact renal function (serum creatinine < 1.2 mg/dL) and only mild proteinuria (< 0.5 g/day) usually are not treated beyond angiotensin inhibition (with ACEi or ARB) and omega-3 fatty acids (fish oil) . Patients with renal insufficiency or more severe proteinuria and hematuria are usually offered treatment, which ideally should be started before significant renal insufficiency develops.