Are there any effective medications for rheumatism?

Condition analysis:
The medications known as biologics that are currently FDA-approved to treat Rheumatoid Arthritis (RA) are etanercept (Enbrel), infliximab (Remicade), adalimumab (Humira), certolizumab pegol (Cimzia), and golimumab (Simponi) [listed in chronologic order of FDA-approval]. A small percentage of people that receive these medications will develop antibodies to the specific drug that may neutralize its effect. This is one possible mechanism for people to experience a diminishing effect of their RA medication. However, typically the biologics produce a durable improvement of disease.

The disease modifying anti-rheumatic drugs (DMARDs), including biologics, improve symptoms in the majority of individuals with RA. However, the degree of response varies between person to person. Thus, even if someone with RA is receiving benefit from a medicine, their response may not be robust enough to cause disease remission.

Additionally, the perception of pain and stiffness can fluctuate for any given person. In your situation, you may still be responding to your medicines, but it is an incomplete response that leaves you vulnerable to fluctuating pain/stiffness symptoms. If you are having an inadequate response to all classes of FDA-approved biologics, your Rheumatologist may try to change your traditional oral DMARDs. For example, some institutions have the ability to check methotrexate levels within a person's body. If subtherapeutic levels are identified then the methotrexate dose or delivery can be changed. Furthermore, RA is an active area of research interest and many innovative medications are being evaluated.

Instructions:
Black Pepper: It’s making me sneeze just thinking about it. But, black pepper has long been known to aid in pain and swelling. You may have heard of capsaicin? Well, that’s the key ingredient in black pepper that’s thought to give rheumatoid arthritis relief. Capsaicin appears in many over the counter creams and lotions – most often associated with anti-inflammatory medications.

he Verdict? Our studies have shown some positive effects of black pepper in treating rheumatoid arthritis. Though, as with most creams and lotions, the relief is only temporary.