Paroxysmal Nocturnal Hemoglobinuria
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TCM Treatment Evaluation for Paroxysmal Nocturnal Hemoglobinuria
1. Deficiency of Spleen and Kidney
Herbal Prescription: Radix Codonopsis (Dangshen), Rhizoma Atractylodis Macrocephalae (Baizhu), Poria (Fuling), Radix Glycyrrhizae (Gancao), Radix Angelicae Sinensis (Danggui), Radix Rehmanniae Praeparata (Shudihuang), Radix Paeoniae Alba (Baishaoyao), Radix Bupleuri (Chaihu), Radix Astragali (Huangqi), Fructus Psoraleae (Buguzhi), Fructus Kochiae (Difuzi)">Fructus Kochiae (Difuzi), Herba Cistanchis (Roucongrong), Herba Artemisiae Scopariae (Yinchen)

2. Deficiency of Qi and Blood
Herbal Prescription: Radix Astragali (Huangqi), Radix Angelicae Sinensis (Danggui), Rhizoma Atractylodis Macrocephalae (Baizhu), Radix Codonopsis (Dangshen), Radix Rehmanniae Praeparata (Shudihuang), Radix Bupleuri (Chaihu), Rhizorna Cimicifugae (Shengma), Citrus aurantium (Chenpi), Herba Artemisiae Scopariae (Yinchen), Poria (Fuling)

3. Retention of Damp-heat in the Interior
Herbal Prescription: Herba Artemisiae Scopariae (Yinchen), Poria (Fuling), Radix Astragali (Huangqi), Radix Glycyrrhizae (Gancao), grifola, Rhizoma Atractylodis Macrocephalae (Baizhu), Rhizoma Alismatis (Zexie), Fructus Gardeniae (Zhizi), Caulk; Akebiae (Mutong), Spica Prunellae (Xiakucao), Radix Isatidis (Banlangen)

Confirmed by clinical manifestations and laboratory data, the principle of differentiation of symptom complexes with regard to the 35 cases was generalized as Shire-Neiyun Gathering and brewing of dampness and heat in the body), Pishen Yang Xu, Insufficiency of vital function of the Spleen and Kidney), Ganshen Yin Xu, Deficiency of vital essence of the Liver and Kidney) and Qizhi Xue Yu, Stagnation of vital energy and stasis of blood),and prescriptions were given correspondingly. Prednisone and androngens, etc., were also used on the part of WM. A 75% effective rate was obtained among the atients. Clinical remission was found in 16 cases with hemolysis markedly alleviated and hemoglobin rising to 10gm%.  A brief discussion on the principle of treatment with TCM as well as problems relating to diagnosis and relapse was made.

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