1. Syndrome of Dampness and Heat in the Liver Meridian
Main Symptoms: Single hard papule in the external genitalia and anus or breast, surrounding swelling, burning sensation in the infected area, white and hard mass in size of apricot kernel or egg in the inguinal groove, bayberry eruption, bayberry nodes or bayberry plaque in the chest, abdomen, lumbus, flexion aspects of the four limbs and neck, accompanied by bitter taste in the mouth, poor appetite, scanty and brown urine, constipation, yellowish and greasy tongue coating, wiry and rapid pulse.

2. Syndrome of Mixture of Phlegm and Blood Stasis
Main Symptoms: Purple red chancre sores with hard and protruded border, or tough bubo, or purple nodular bayberry sores, or belly as hard as a brick, hepatosplenomegaly, slightly purple tongue or dark tongue, greasy or moist coating, slippery or thready and hesitant pulse.

3. Syndrome of Dampness Accumulation due to Spleen Deficiency
Main Symptoms: Ruptured chancre sores, slight moist in the surface, or extensive ulceration, brown dark in the skin color, or dermal boils with discharge of yellowish fluid, or falling putrid flesh, without healing for a long time, accompanied by soreness and pain in the tendons and bones, stuffy chest, poor appetite, loose stool, fatigue in the limbs and heavy sensation in the body, flabby and moist tongue, greasy coating, slippery or soft pulse.

4. Syndrome of Qi and Blood Deficiency
Main Symptoms: Long duration, pale granulation in the ulcerous surface, with thin purulent fluid and without healing for a long time, withered yellowish complexion, accompanied by dizziness, blurred vision, palpitation, anxiety, short breath, reluctance to speak, pale tongue, thin coating, thready and forceless pulse.