Symptoms of neuromyelitis optica (NMO) can include all of the following, although visual symptoms and spinal cord inflammation (transverse myelitis) are primary. Abrupt changes in vision caused by optic neuritis include:

Loss or blurring of vision in one or both eyes
Loss of color vision
Eye pain

Changes in sensation and function in the limbs caused by transverse myelitis, which usually affects multiple levels in the spinal cord, include:

Weakness
Numbness (loss of sensation)
Loss of function (paralysis)
Loss of blowel or bladder control
retention of urine or difficulty emptying the bladder
Spasticity (increased tone or stiffness in the extremities)
Shooting pain or tingling in the neck, back or abdomen
Uncontrollable nausea and vomiting
Uncontrollable hiccups
Fatigue
Confusion, seizures or coma can occur in children