It's not clear why some people develop chronic inflammation or why ongoing inflammation triggers polyp formation in some people and not in others. The inflammation occurs in the fluid-producing lining (mucous membrane) of your nose and sinuses. There's some evidence that people who develop polyps have a different immune system response and different chemical markers in their mucous membranes than do those who don't develop polyps.

In TCM, the pathogenic factors of the disease are mainly the allergic reactions and stimulation of chronic inflammation of the nasal cavity and nasal sinuses. Nasal polyp was originally a name in TCM. Besides, it is also called "Bizhi" (nasal hemorrhoid) in TCM. When dampness or dampness and heat stagnates, pathogenic dampness and heat will accumulate in the nose. If the state lasts long without the dispersion of dampness and heat, dampness and heat will coagulate, forming polyp.