Treatment of Von Hippel-Lindau syndrome
In general, treatment for kidney cancer is similar regardless of whether a patient has VHL. However, there is some evidence about specific VHL considerations regarding  surgery. For a person with VHL and kidney cancer, surgery for a kidney tumor is generally considered when a tumor reaches 3 centimeters (cm) in size. Preserving the kidney’s function with the intent of preventing or delaying dialysis is an important part of the current surgical approach to VHL, and surgeons generally try to remove kidney tumors while trying to leave as much normal kidney behind as possible (called nephron sparing surgery or partial nephrectomy). Similarly, the main treatment for tumors arising in other organs is also surgery, which is done when the tumor reaches a specific size or causes symptoms.