What are symptoms of myeloproliferative disorders?

Condition analysis:
There are 3 main types- essential thrombocytosis (et), polycythemia vera (pv) and myelofibrosis (mf). In et, there is increased clotting and risk for strokes. In pv, there is generalized itchiness, ruddy face, and stroke risk. In mf, patients get low blood counts over time causing fatigue, large spleen, poor appetite, abdomen pain, transfusion need.

Instructions:
Causes of myeloproliferative disorders
General: Myeloproliferative disorders occur when the body produces too many of one or more types of blood cells. However, the reason for this remains unknown. Researchers believe that genetics and/or the environment may play a role in the development of these disorders.

Genetics: Some people with chronic myelogenous leukemia (CML) have been shown to have a shortened chromosome, called the Philadelphia chromosome. Chromosomes contain a person's genetic makeup, called DNA. This abnormality suggests that genetics may play a role in some types of myeloproliferative disorders.