What research is being done on myasthenia gravis?

Condition analysis:
Within the federal government, the National Institute of Neurological Disorders and Stroke (NINDS), one of the federal government's National Institutes of Health (NIH), has primary responsibility for conducting and supporting research on myasthenia gravis.

Much has been learned about myasthenia gravis in recent years. Technological advances have led to more timely and accurate diagnosis, and new and enhanced therapies have improved management of the disorder. Much knowledge has been gained about the structure and function of the neuromuscular junction, the fundamental aspects of the thymus gland and of autoimmunity, and the disorder itself. Despite these advances, however, there is still much to learn. The ultimate goal of myasthenia gravis research is to increase scientific understanding of the disorder. Researchers are seeking to learn what causes the autoimmune response in myasthenia gravis, and to better define the relationship between the thymus gland and myasthenia gravis.

Today's myasthenia gravis research includes a broad spectrum of studies conducted and supported by NINDS. NINDS scientists are evaluating new treatments, and improving current treatments for the disorder. One such study is testing the efficacy of intravenous immune globlin in patients with myasthenia gravis. The goal of the study is to determine whether this treatment safely improves muscle strength. Another study seeks further understanding of the molecular basis of synaptic transmission in the nervous system. The objective of this study is to expand current knowledge of the function of receptors and to apply this knowledge to the treatment of myasthenia gravis.

Instructions:
Eye patches: Wearing an eye patch from time to time may help reduce eye weakness because symptoms are worsened by physical activity. Some doctors may recommend wearing a single eye patch when reading or watching television and switching it between eyes periodically.

Occupational therapy: Patients may benefit from occupational therapy. These therapists may be able to recommend different ways to perform tasks or certain devices (e.g. Velcro? fasteners) to make daily activities easier. Patients can ask their doctors to recommend therapists.