Expert ReplyCondition analysis:
Conventional treatment aims to shrink the polyps using steroids, before surgery is considered. Often doctors will attempt a "medical polypectomy", by giving a one to two week course of oral steroids, followed by three or four weeks of antibiotics, and then long-term use of intranasal steroids. Surgery requires a nasal endoscopy and often has to be performed due to inadequate response from the cocktail of medicines. Doctors try to further minimise the chance of the polyps returning by prescribing nasal steroids indefinitely after surgery (5). Long term use of steroids are detrimental to the person's overall health and can have side effects including osteoporosis, growth retardation in children and thinning skin.
Instructions:
People with chronic rhinosinusitis and nasal polyps are at increased risk of vitamin D deficiency. In addition to this, vitamin D deficiency is associated with worsened symptoms. One study found that when patients supplemented with vitamin D they had a decrease in human sinonasal fibroblast (HSNF) activity compared to control. Elevated levels of HSNF are associated with chronic rhinosinusitis and thought to play a major role in disease activity.