What is primary sclerosing cholangitis (PSC)

Condition analysis:
PSC is an uncommon condition that affects the bile ducts and liver. It is called:
-- Primary - because the cause is not known. (That is, it is not 'secondary' to any known cause such as alcohol or poisons.)
-- Sclerosing - because it causes scarring and thickening (sclerosis) of the bile ducts.
-- Cholangitis - which means inflammation of the bile ducts.

In this condition, the bile ducts both inside and outside the liver become inflamed and scarred. The scarring causes narrowing of these bile ducts which results in bile building up in the liver. The bile can then damage the liver cells. Eventually, the scar tissue can spread throughout the liver, causing cirrhosis and liver failure. Cirrhosis is a serious condition where normal liver tissue is replaced by scar tissue (fibrosis). It tends to progress slowly and often does not cause symptoms in its early stages. However, as the function of the liver gradually becomes worse, serious problems can develop. See separate leaflet called Cirrhosis for more details.

Instructions:
If you've been diagnosed with primary sclerosing cholangitis, take steps to care for your liver, such as:
Don't drink alcohol.
Get vaccinated against hepatitis A and B.
Use care with chemicals at home and at work.
Maintain a healthy weight.
Follow directions on all medications, both prescription and over the counter. Make sure your pharmacist and any doctor prescribing for you know that you have a liver disease.
Talk to your doctor about any herbs or supplements you're taking since some can be harmful to your liver.