Edema is observable swelling from fluid accumulation in body tissues. Edema most commonly occurs in the feet and legs, where it is referred to as peripheral edema. The swelling is the result of the accumulation of excess fluid under the skin in the spaces within the tissues. All tissues of the body are made up of cells and connective tissues that hold the cells together. This connective tissue around the cells and blood vessels is known as the interstitium. Most of the body's fluids that are found outside of the cells are normally stored in two spaces; the blood vessels and the interstitial spaces. In various diseases, excess fluid can accumulate in either one or both of these compartments. Common causes of edema include:
--Burns
--Certain medications
--Cirrhosis
--Congestive heart failure
--Damage to lymph nodes due to surgery or radiation therapy
--Excessive salt consumption
--High blood pressure
--Kidney disease
--Parasitic infection such as lymphatic filariasis
--Pregnancy
--Alcoholism
--Cancer
--High blood pressure
--Kidney disease
--Liver failure