It is believed in Chinese medicine that this disease belongs to the category of "Breast Mass" and "Nodule in Breast",mostly caused by emotional injury, accumulation of liver qi, qi stagnation and blood stasis, blockage of the collaterals of the breast, or over fatigue, insufficiency in the liver and kidney, disharmony of the Thoroughfare Vessel and Conception Vessel, and accumulation of phlegm due to qi stagnation. In addition, this disease can also be caused by improper food intake, failure of the spleen in transportation, mixture of phlegm and stasis in the collaterals of the breast. Clinically, the onset and changing rule of hyperplasia of mammary lobule are closely related to changes in menstrual cycle and emotion, and accumulation of phlegm due to stagnation of liver qi is the main pathogenesis.Consequently, it is necessary to adhere to the therapeutic principle to soothe the liver, relieve stagnation, dissolve phlegm and disperse accumulation in the clinical treatment.