The disease results from the congenital insufficiency and postnatal improper nursing. It mostly belongs to asthenia syndromes, mainly asthenia of the heart, spleen, liver, and kidney. Insufficiency of renal essence and bone marrow makes the head lose its nourishment; some infantile patients postnatally suffer from blood stasis and phlegm obstructing cerebral collaterals, giving rise to mental deficiency.According to the theory of traditional Chinese medicine, there are some patterns of syndrome that lead to hypophrenia.1. Asthenia of the liver and kidney 2. Deficiency of heart blood 3. Blood stasis obstructing cerebral collaterals