Ingredients:
No.1  Shengdihuang (Radix Rehmanniae Recens) 6 g
No.2  Mutong (Caulis Akebiae) 6 g
No.3  Shenggancaoshao (Radix Glycyrrhizae) 6 g

Administration:
These ingredients are ground into powder. Each time 9g is decocted with proper amount of Zhuye (Herba Lophatheri) for oral administration.

Actions:
Removing heart fire and inducing diuresis.

Clinical Application:
This recipe is applicable to intense heat syndrome in the heart meridian, manifested as irritability, feverish sensation in the chest, thirst, flushed face, preference for cold drinks, oral ulceration; or dark urine with difficulty and pain in urination, red tongue with thin yellowish fur, and rapid pulse. It can be used to deal with stomatitis, thrush, infantile night cry and infantile urinary infection, which pertain to domination of heat in the heart meridian.

In case of excessive fire in the heart manifesting dysphoria and much aphthae, add Huanglian (Rhizoma Coptidis) to enhance the action of clearing the heart and purging fire; in case of dark urine with difficulty and burning pain in urination, which is indicative of heat invading the small intestine, add Cheqianzi( Semen Plantaginis) and Chifuling (Poria Rubra) to promote diuresis; if used for infantile night cry, add Fushen (Sclerotium Poriae Circum Radicem Pini) and Suanzaoren (Semen Ziziphi Spinosae) to tranquilize the mind.

Elucidation:
The syndrome is result of flaming up of the heart-fire due to accumulation of heat in the heart meridian or heat in the heart invading the small intestine. It should be treated by clearing away heat and fire from the heart and promoting diuresis. Ingredient No. 2 is to purge pathogenic fire from the heart, promote urination and induce downward heat in the heart, acting as monarch drug. Ingredient No. 1 is meant to purge away heat from the heart, nourish yin and promote the production of body fluid, and when combined with ingredient No. 2, it can prevent impairment of yin, serving as minister drug.

Zhuye (Herba Lophatheri) is for reducing heat from the heart, relieving restlessness, inducing heat downward, and plays the part of adjuvant drug. Ingredient No. 3 can clear away heat, relieve painful urination and coordinate the actions of various ingredients in the recipe, acting as guiding drug. All the ingredients in combination achieve the effect of clearing away heat from the heart, promoting urination without impairing yin and nourishing yin without retaining pathogenic factors. Such symptoms as dysphoria, aphthae and painful urination will disappear when heat in the heart is induced downward and out through urination.

This prescription is forbidden to use to treat patients with exuberant heat not in the heart meridian or patients with renal insufficiency since Sanye Mutong (Radix clematidis Trifolium), Chu Mutong (Caulis Clematidis Armandii) and Guan Mutong (Caulis Aristolochiae Manshuriensis) are all used as drugs. But Guan Mutong contains aristolochine. Large dosage of preparation containing Guan Mutong (over 10 g daily) may damage the kidney. So this prescription should not be used for a longer period of time.