Essential thrombocytosis, which is also called primary thrombocytosis, is a non reactive chronic myeloproliferative disorder. This disorder is associated with sustained megakaryocytic proliferation which increases the number of circulating platelets. Earlier, this disorder was considered a clonal disease which involved stem cells but according to certain recent studies, some patients may have polyclonal hematopoietic as well. In simple words, this is a disorder in which the body produces too many blood platelets. There are several signs and symptoms of this condition and treatment is generally required only when these symptoms are identified.

Patients with essential thrombocythemia may have the following symptoms:
1. Skin problems such as redness, burning, or itching
2. Pain in the feet and hands
3. A mildly enlarged spleen
4. Headache, dizziness, weight loss
5. Abnormal bleeding
6. Pregnancy complications
7. Abnormal blood clotting