Integration of Chinese medicine and western medicine would be a good choice for this disease. When treating Erythema Nodosum, Chinese doctors will take everything into consideration.
1. Syndrome of Stagnation and Obstruction of Dampness and Heat
2. Qi Stagnation and Blood Stasis Syndrome

In TCM, the pathogenesis is still unknown and may be a kind of delayed allergic reaction or disease of immune complex. This disease is similar to"Multiple Abscess of Damp Toxin" and "Gua Teng Chan (Erythema Nodosum)" in Chinese medicine, induced and repeatedly broken out by production of fire due to long accumulation of dampness, obstruction of the meridians and collaterals due to downward transmission of dampness and heat, or by blockage of the meridians and collaterals due to long-term sickness, leading to qi stagnation and blood stasis.