Malabsorption Syndrome is an alteration in the ability of the intestine to absorb nutrients adequately into the bloodstream. Malabsorption may be due to an abnormality of the gut wall, failure to produce enzymes or bile to aid digestion, or there may be abnormalities of the flora of the gut. Malabsorption may occur for many nutrients or for specific carbohydrates, fats or micronutrients. Protein, fats, and carbohydrates normally are absorbed in the small intestine - the small bowel also absorbs about 80 percent of the eight to ten liters of fluid ingested daily.

Many different conditions affect fluid and nutrient absorption by the intestine. A fault in the digestive process may result from failure of the body to produce the enzymes needed to digest certain foods. Congenital structural defects or diseases of the pancreas, gall bladder, or liver may alter the digestive process. Inflammation, infection, injury or surgical removal of portions of the intestine may inhibit absorption abilities. Reduced length or surface area of intestine available for fluid and nutrient absorption can also result in malabsorption.

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