Causes of Coagulation Disorders based on Chinese medicine
In traditional Chinese medicine, blood disease (trouble) is formed due to four contributing factors: 1) Inborn deficiency: loss of kidney essence and hyperactivity of liver fire damaging the veins is one of the main causes of coagulation disorders. 2) Injury of the seven emotions: excessive thingking and anger can lead to depressed liver or hyperactivity of liver, resulting in the injury of veins and hemorrhage. 3) Improper diet: heavy foods alcohol may cause damp-heat damaging spleen and stomach, leading to hemorrhage. 4) Excessive fatigue: This may damage the heart, spleen, and kidney. When qi is damaged, it fail to control blood, resulting in hemorrhage.

Causes of Coagulation Disorders in western medicine
Coagulation disorders deal with disruption of the body's ability to control blood clotting. The most commonly known coagulation disorder is hemophilia, a condition in which patients bleed for long periods of time before clotting. There are other coagulation disorders with a variety of causes. Normal blood clotting involves blood components called platelets and as many as 20 different plasma proteins. These are known as blood clotting or coagulation factors. These factors interact with other chemicals to form a substance called fibrin that stops bleeding. Problems can occur when certain factors are low or missing. Bleeding problems can range from mild to severe. Some bleeding disorders are present at birth and are passed through families (inherited). Others develop from:

1) Illnesses such as vitamin K deficiency or severe liver disease
2) Treatments such as the use of drugs to stop blood clots (anticoagulants) or the long-term use of antibiotics

Bleeding disorders can also result from a problem with the number or function of the blood cells that promote blood clotting (platelets). These disorders can also be either inherited or develop later (acquired). The side effects of certain drugs often lead to the acquired forms.