Glomerulonephritis is a disease that causes inflammation of the kidney’s tiny filtering units called the glomeruli. Glomerulonephritis usually happen suddenly in most cases following an infection. For example, after a streptococci infection of the throat and Most cases the individual recovers from the infection. However, the disease may develop slowly over several years. Other causes is normally existing antibody is deposited in the glomeruli and incites inflammation which may cause progressive loss of kidney function.Glomerulosclerosis refers to scarring of the glomeruli. It may be caused by the diseases such as diabetic nephropathy, IgA disease, or lupus nephritis. Focal segmental glomerulosclerosis (FSGS) is one such condition. Sometimes a cause can be found, other times it is not known (idiopathic).