Depletion of qi with bleeding refers to syndrome in which qi depletes due to massive bleeding. This syndrome is usually caused by trauma, or by damage of the viscera, or by massive bleeding from uterus or in delivery of child.
 
Clinical manifestations:
Massive bleeding accompanied by pale complexion, profuse sweating, cold limbs, weak breath, extreme dispiritedness, even coma, pale tongue, indistinct pulse, or hollow pulse, or scattered pulse.

Analysis of symptoms:
Blood is the mother of qi, so loss of blood will lead to loss of qi at the same time; pale complexion and cold limbs are due to loss of qi and yang to warm the body; profuse sweating is due to sudden loss of yangqi which weakens the superficies and gives rise to leakage of fluid weak breath, extreme dispiritedness and even coma are due to loss of proper nutrition of the spirit resulting from depletion of qi and blood; indistinct pulse or hollow pulse or scattered pulse are due to loss of qi and blood that disperses primordial qi and fails to enrich the vessels; pale tongue is the sign of consumption of qi and blood which fail to nourish the head.

Key points for syndrome differentiation:
Massive bleeding and simultaneous loss of qi and blood.